March 23, 2026 – Smile Study

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Day: March 23, 2026

Day: March 23, 2026

Vaping and the oral microbiome: changes observed, but no clear evidence of harm

March 23, 2026 No Comments

SMILE is an international, open-label randomized controlled study designed to assess whether cigarette smokers who switched to combustion-free nicotine delivery systems (C-F NDS) underwent measurable improvements in oral health parameters and teeth appearance as a consequence of avoiding exposure to cigarette smoke.

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© 2026 Smile Study is a CoEHAR investigator-initiated research. It is funded by ECLAT Srl (University of Catania spin-off) through a competitive grant from Global Action to End Smoking, a U.S. nonprofit 501(c)(3) private foundation. Global Action had no role in the planning or execution of this study, data analysis, or publication of results.